Some Important Hepatoprotective Medicinal Plants In Ayurveda- A Review

Authors

  • Kiran Paudel P.G. Scholar, P.G. Department of Dravyaguna Vigyana, NIA, Jaipur Author
  • A Ramamurthy Professor., P.G. Department of Dravyaguna Vigyana, NIA, Jaipur Author
  • Gaurav Sharma Pharmacologist, P.G. Department of Dravyaguna Vigyana, NIA, Jaipur Author

DOI:

https://doi.org/10.48165/

Keywords:

Medicinal Plants, Hepatoprotective Medicinal Plants, Traditional Medicine, Herbal Drugs

Abstract

The liver is the chief site of Metabolism of nutrients and energy production in the human body.  Environment, pathogenic micro-organisms, viruses, drugs and chemical agents are the main factors of the  many type of Liver disease. Hepatic necrosis, Hepatitis, Liver fibrosis and Liver cirrhosis etc. are the  common disease found in the community related to the liver. Berberis aristata, Andrographis paniculata,  Achyranthes aspera etc. plants are renowned for their satisfactory activity against certain hepatic related  diseases. About 80% of the world population relies on the use of traditional medicine, which is  predominantly based on plant material. The present review discusses different types of medicinal plants  in Ayurveda containing hepatoprotective activity with other important activities too. Therefore, the present  review is aimed to compiling data on hepatoprotective medicinal plants. 

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References

Mauss S, Berg T, Rockstroh J, Sarrazin C et al. Hepatology: A Clinical Textbook. 9th Edition. 2018.

Girish C, Koner BC, Jayanthi S et al. Hepatoprotective activities of six polyherbal formulations in paracetamol induced liver toxicity in mice. Indian J Med Res. 2009;129(5):569-572.

Pushpangadan P, Iyengar PK, Damodaran VK, Pushpagadan P Editors. Role of Traditional Medicine in Primary health Care In Science for Health. Kerala: State Committee On Science, Technology And Environment, Govt. of Kerala;1995.

Aszalos A. Antitumor Compounds of Natural Origin. Boca Raton, CRC Press; 1982. 5. Sumeet D, Raghavendra D and Kushagra M. Achyranthes aspera Linn. (Chirchira): A magic herb in folk medicine. Ethnobotanical Leaflets. 2008;12:670-676. 6. Srivastav S, Singh P, Mishra G et al. Achyranthes aspera An important medicinal plant: A review. JNPR. 2011;1:11-14.

Chakrabarti R, Srivastav PK, Kundu K et al. Evaluation of immunostimulatory and growth promoting effect of seed fractions of Achyranthes aspera in common carp Cyprinus carpio and identification of active constituents. Fish and shellfish Immunology. 2012;32:839-43.

Kunert O, Haslinger E, Schmid MG, Reiner J et al. Monatshefte fur chemie. 2000;131:195-204.

Rastogi PR & Mehrotra BN. Compendium of Indian Medicinal Plants. Central Drug Research Institute, Lucknow and National institute of science communication and information resources, New Delhi. 2004; 11:7-8.

George KV & George KV. In-vitro Studies on Antilithiatic Property of Achyranthes aspera. Journal of Pharmacy Research. 2012;5:4366-4370.

Srivastava PK. Achyranthes aspera: A potent immunostimulating plant for traditional medicine. IJPSR. 2014;5(5):1601-1611.

Nadkarni KM. Indian Materica Medica. Bombay Popular Prakashhan: 2009;I(21). 13. Khare CP. Indian Medicinal Plants. Springer: 2007;11-13.

Anonymous, The wealth of india-Raw Materials, Council of Scientific and Industrial Research (CSIR), New Delhi: 2007;17-18.

Mishra SK, Sangwan NS, Sangwan RS. Andrographis paniculata (Kalmegh): A review. Pharmacognosy Reviews. 2007;1:283-298.

Kabeeruddin M, Kitabul Advia. Aligad Barqi Press:Delhi;1937;148-150. 17. Sahid A, Andrographis paniculata: A review of pharmacological activities and clinical effects. Alternative Medicine Review. 2011;16:66-77.

Abhishek N et al. Biological activities of Kalmegh (Andrographis paniculata Nees.) and its active principles- A review. 2010;1(2):125-135.

Sahid A. Andrographis paniculata: A review of pharmacological activities and clinical effects, Alternative Medicine Review. 2011;16:66-77.

Singha PK, Roy S, Dey S. Protective activity of andrographoide and arabinogalactan proteins from Andrographis paniculata Nees. against ethanol-induced toxicity in mice. J Ethanopharmacol. 2007; 111:13-21.

Choudhary BR, Poddar MK. Effect of Kalmegh extract on rat liver and serum enzymes. Methods Find Exp clin Pharmacol. 1983;5:727-730.

Dai Y, Chen SR, Chal et al. Overview of Pharmacological Activities of Andrographis paniculata and its Major Compound Andrographolide. Crit Rev Food Nutr. 2018;59(1):S17-29.

Ali M, Malik A, Sharma KR, Vegetative propagation of Berberis aristata DC. An endangered Himalayan shrub. J Med Plants Res. 2008;2:374-7.

Ambustha SP. Ambustha SP editor. The Wealth of Indian Berberis Linn. (Berberidaceae). New Delhi: Publication and Information Directorate, CSIR;1988,p.114-8.

Srivastava S, Rawat A. Quality evaluation of Ayurvedic crude drug daruharidra, its allied species, and commercial samples from herbal drug markets of india. Evid Based Complement Alternat Med. 2013;2013:1-14.

Wallis TE. Practical Pharmacognosy London: J and A Churchill Ltd. 1946.p.185-6. 27. Ernodubov AI, Betestovaja MM. The Wealth of India A dictionary Indian Raw Materials and Industrial Products, Raw materials. New Delhi. Council of Scientific and Industrial Research, CSIR; 2007. p.135.

Ministry of Health and Family Welfare, Government of India, Department of Indian System of Medicine and Homopathy. The Ayurvedic Pharmacopia of India. Part Ist ed. Vol.I. New Delhi;2001.p.139.

Ministry of Health and Family Welfare, Government of India, Department of Indian System of Medicine and Homopathy. The Ayurvedic Pharmacopia of India. Part. Ist, Vol. I. New Delhi;1996.p.143.

Affuso F, Mercurio V, Fazio V, Fazio S. Cardiovascular and metabolic effects of berberine. World J cardiol. 2010;2:71-7.

Ansari SH. Essentials of Pharmacognosy. 1st ed. Birla Publication Pvt. Ltd:New Delhi;2005.p.357-84.

Bhakuni DS, Shoeb A, Popli SP. Studies in Medicinal plants: Part I-Chemical constituents of Berberis asiatica Roxb. Indian J Chem. 1968;6:123.

CSIR. The Wealth of India: A dictionary Indian Raw Materials and Industrial Products Raw Materials. Vol. I. A-I. New Delhi: Council of Scientific and Industrial Research;2007.p135.

Potdar D, Hirwani R, Dhulap S. Phyto-chemical and Pharmacological applications of Berberis aristata. Fitoterapia. 2012;83:817-30.

Rastogi RP, Mahrotra BN. Compendium of Indian Medicinal Plants. Vol. 3. New Delhi: CDRI Lucknow and PID CSIR;1993;p.3.

Indian Herbal Pharmacopoeia. Mumbai: Indian Drugs manufacturing Association (Regional Research Laboratory Jammu Tavi);1999;p.1,33.

Lamichhane B, Adhakari S, Shrestha P, Shrestha BG. Study of Phytochemical, antioxidant, antimicrobial and anticancer activity of Berberis aristata. J Trop Life Sci. 2014;4:1-7.

Pareek A, Suthar M. Anti-diabetic activity of extract of Berberis aristata root in steptozocin induced diabetic rats. Pharmacologyonline. 2010;2:179-85. 39. USDA, ARS, National Genetic Resources Program. Germplasm Resources Information Network-(GRIN). National Germplasm Resources Laboratory, Beltsville, Maryland. URL: http://www.ars-grin.gov.4/cgi-bin/npgs/html/taxon. pl?10543 (18 June 2015) 40. Flora of China, www.efloras.org, http://www.efloras.org/florataxon.aspx?flora.

Nandagopa S, Ranjitha Kumari F. Phytochemical and antibacterial studies of chicory (Cichorium intybus L.): A multipurpose medicinal plant. Advances in Biological Research. 2007;1(1-2):17-21.

Mushtaq A, Ahmad M, Jabeen Q. Pharmacological role of cichorium intybus as a hepatoprotective agent on the elevated serum marker enzymes level in albino rats intoxicated with nimesulide. Int J Curr Pharm Res. 2013;5(3):25-30.

Shad MA, Nawaz H, Rehman T et al. Determination of some biochemicals, phytochemicals and antioxidant properties of different parts of Cichorium intybus L.: A comperative study. The journal of Animal & Plant Sciences. 2013;23(4):1060-1066.

Street RA, Sidana J, Prinsloo G. Cichorium intybus: traditional uses, phytochemistry, pharmacology and toxicology. Evidence-Based Complementary and Alterantive Medicine. 2013; http://dx.doi.org/10.1155/2013/579319.

Judzentiene A, Baidiene JB. Volatile constituents from aerial parts and roots of Cichorim intybus L. (Chicory) grown in Lithuania. Chemija. 2008;19:25-28. 46. Plant Database Facts Sheet (http://www.plantdatabase.net/Mahonia nepalensis) (Accessed 27 April, 2013)

Polium O, Stainton A: Flower of Himalaya. Oxford University Press, Oxford India paperbacks:20-22.

Govindachari TR, Pai BR, Rajadurai S, Rao UR. Alkaloides of Mahonia nepalensis DC. J Ind Chem Soc. 1957;41-48.

Nguyen TM, Tran AT, Hoang TH et al. Bisbenzylisoquionoline Alkaloide from Mahonia nepalensis, J Chem. 2009;46(5):63-68.

Nguyen TM, Tran AT, Hoang TH et al. Bisbenzylisoquionoline Alkaloide from Mahonia nepalensis, J Chem. 2009;47(3):365-370.

Khatune NA, Mosaddik MA, Haque ME. Antibacterial activity and cytotoxicity of Nyctanthes arbor-tristis flowers. Fitoterapia. 2001;72:412-4.

Central Council for research In ayurveda and siddha. Database of Medicinal plants used in ayurveda, CCRAS. 2002;4:470-483.

Puri A, Saxena R, Saxena RP et al. Immunostimulant activity of Nyctanthes arbor tristis L. Journal of ethnopharmacology. 1994;42:31-7.

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Rani C, Chawla S, Mangal M et al. Nyctanthes arbor-tristis Linn. (Night Jasmine): A sacred ornamental plant with immense medicinal potentials. Indial J Tradit Knowl. 2012;11:427-35.

Bansal G, Suri KA, Gorver A. comprehensive review on Nyctanthes arbor-tristis, Int J. Drug Dev. & Res. 2015;7:1-8.

Fallah H, Zarrei M and Ziai M. The effects of Taraxacum officinale L. and Berberis vulgeris L. root extracts on carbon tetrachloride induced liver toxicity in rats. J Med Plants. 2010;9:45-52.

Mahesh A, Jeyachandran R, Cindrella L et al. Hepatoprotective potential of sesquiterpene lactones of Taraxacum officinale on carbon tetrachloride induced liver toxicity in mice. Acta Biol Hung. 2010;61:175-190.

Cordatos E. Taraxacum officinale. In: Murray M, Pizzorno J, eds. A Textbook of Natural Medicine. Seattle: Bastyr University Press;1992.

Williams CA, Goldstone F, Greenham J. Falvenoids, cinnamic acids and coumarins from the different tissues and medicinal preperations of Taraxacum officinale. Phytochemistry. 1996;42:121-127.

Sharma K & Zafar R: Occurrence of taraxerol and teraxasterol in medicinal plants, Pharmacognosy Reviews. 2015;9:19-23.

Randhawa GS & Mukhopadhyay A. Floriculture in India. Allied Publishers Private Limited. 1986;225.

Verma KS, Jain AK & Gupta SR. Structures of Undulatine: A new Iridoid Glucoside from Tecomella undulata. Plant Med. 1986;5:359-62.

Joshi KC, Singh P & Pardasani RT. Quinines and other constituents from the roots of Tecomella undulata. Planta Med.1977;31(1),14-6.

Rahmatullah M, Samarrai W, Jahan R et al. An Ethnomedicinal, Pharmacological and Phytochemical Review of some Bignoniaceae Family Plants and Description of Bignoniaceae Plants in Folk Medicinal Uses in Bangladesh. Advances in Natural and Applied Sciences. 2010;4(3):236-253.

Ahmad F, Khan RA, Rasheed S. Preliminary screening of methonolic extract of Celastrus paniculatus and Tecomella undulata for analgesic and anti-pyretic activities. Journal of Ehtnopharmacology. 1994;42:193-198.

Khatri A, Garg A, Agrawal SS. Evaluation of hepatoprotective activity of aerial part of Tephrosia purpuria L and stem bark of Tecomella undulata. Journal of Ethnopharmacology. 2009;122:1-5.

Kritikar KR, Basu BD, Basu ML. Indian Medicinal plants. Allahabad, India;1956;3:2322-2324.

Jain A, Singhai AK & Dixit VK. comparative study of ethanol extract of leaves of Tephrosia purpurea and the flavonoid isolated for hepatoprotective activitiy. Indial J of pharmaceutical. 2007;312-315.

Larson RA. The antioxidant of higher plants, phytochemistry. 1994;27(4):969-978. 70. Patel A, Patel A, Patel NM. Estimation of flavonoid, polyphenolic content and In-vivo antioxidant capacity of leaves of Tephrosia purpurea Linn. (Leguminosae). IJPSR. 2010;1(1):66-77.

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Published

2020-08-31

How to Cite

Paudel, K., Ramamurthy, A., & Sharma, G. (2020). Some Important Hepatoprotective Medicinal Plants In Ayurveda- A Review. International Research Journal of Ayurveda & Yoga, 3(8), 138-150. https://doi.org/10.48165/