A Review on Pramehahara Dravya of RajaNighantu

Abstract

Background: Nighantus plays an important role in Ayurveda as they give knowledge about herbo-mineral drugs  and describe their properties in easy manner. There are many drugs described in Brihatrayee and Laghutrayee which  show Pramehahara effects. After Samhita period, many Nighantus came. RajaNighantu as per name is the raja  of all Nighantus. There are 23 Varga’s in RajaNighantu. Prameha is the Santarpana Janya Vyadhi. Twenty types  of Prameha are described in Charaka Samhita, which includes 10 types of Kaphaj Prameha, six types of Pittaj  Prameha, and four types of Vataj Prameha. Diabetes mellitus can correlate with Madhumeha, which is a type of  Vataj Prameha. Purpose: This study’s goal is to compile a list of RajaNighantu’s beneficial herbs for Prameha/DM. Materials and Methods: Journals, the internet, and other appropriate ayurvedic and modern literatures were used in  addition to RajaNighantu to gather knowledge on the subject. Results and Discussion: RajaNighantu described 51 dravyas for the treatment of Prameha. Among them 37  Audbhida dravya, seven Parthiva dravya, and four Jangam dravya as Pramehahara. Apart from these, Shritasita  jala, Puranaguda, and Madhavi madya are also described as Pramehahara. According to the Rasa, 15 had Madhur rasa, 13 had Tikta rasa, seven had Katu rasa, four had Kashaya rasa, one had Amla rasa, and one had Lavan rasa,  respectively. Diabetes mellitus (DM) describes a collection of related metabolic  disorders that are characterized by hyperglycemia. Genetics and  environmental factors combine intricately to generate multiple kinds  of DM. Reduced insulin secretion, decreased glucose utilization, and  increased glucose production are some of the factors that contribute to  hyperglycemia, depending on the etiology of the diabetes. The metabolic  dysregulation linked to DM results in secondary pathophysiologic  alterations in various organ systems, which significantly impact both  the diabetic patient and the health-care system.[1] India is becoming  the global hub for diabetes due to the rising prevalence of this illness.