A comparison of Volatile Organic Compounds (VOCs) and the Concept  of Gandha with special reference to Balagraha

M K Lekshmi; Revathi S Nair

doi:10.48165/

Authors

M K Lekshmi Associate Professor,Department of Kaumarabhritya, Government Ayurveda College, Thiruvananthapuram, Kerala Author
Revathi S Nair PG Diploma scholar, Department of Kaumarabhritya, Government Ayurveda College, Thiruvananthapuram, Kerala Author

DOI:

https://doi.org/10.48165/

Keywords:

Volatile organic compounds, balagraha, infectious diseases, gandha

Abstract

The ancient science of Ayurveda has many unique concepts regarding the creation of the living, health issues, diseases and their treatment. These are distinctive and have the scope to incorporate modern development into them. During the trying times of the recent pandemic, there has been the development of sensors for detecting VOCs (volatile organic compounds) produced by COVID-infected individuals which helped to diagnose the disease swiftly to minimize its spread. The interaction between pathogenic viruses in respiratory tract infection and the body's microenvironment produces distinctive volatile organic compounds (VOCs). VOCs are gaseous molecules released as a product of metabolic processes in the body whose composition changes directly as a result of pathologic processes, such as an infection. This concept of different body odours in physiological and pathological conditions has been mentioned in Ayurveda thoroughly, especially in the context of Balagraha (which can be correlated to various infectious diseases). This shows the science's proficiency to be way ahead of its time. Thus, the incorporation of such distinctive ayurvedic concepts will help in the comprehensive development of the medical sciences.

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References

Sharma S.P, Ashtanga sangraha, with Shashilekha Sanskrita commentary by Indu, Sutrasthanam, 17/2 Published by Chaukhamba Sanskrita Sansthana Varanasi 2006.

Malik DK. Panchamahabhuta - Aadharbhut Siddhant and their application in Chikitsa. J Ayurveda Integr Med Sci. 2018;3(5).

Article R. A critical review of fundamental principles of ayurveda. Int Ayurvedic Med Journal(IAMJ). 2015;3(7):2075–83.

Pai KU, Critical analysis on physiological understanding of Indriya. 2015;3(7):2075–83.

Farosh SM, Importance of Ghranendriya as explained in Ayurveda with reference to Olfaction. 2015;3(7):2075–89 6. Abraham A. International Journal of Ayurveda CATARACT-A CLINICAL STUDY. 2020;8(1):13–21. 7. Tripathi B, Ashtanga Hridaya, Sutrasthana 1/5 Published by Chaukhambha Sanskrita Pratishtana Delhi 2012.pp.5 8. Tripathi B, Ashtanga Hridaya, uttartantra 3/1 Published by Chaukhambha Sanskrita Pratishtana Delhi 2012.pp.899. 9. Tripathi B, Ashtanga Hridaya, uttartantra 3/40-41 Published by Chaukhambha Sanskrita Pratishtana Delhi 2012.pp.904.

Tripathi B, Ashtanga Hridaya, uttartantra 3/4-5 Published by Chaukhambha Sanskrita Pratishtana Delhi 2012.pp.901.

Sharma S, Ashtanga sangraha, with Shashilekha Sanskrita commentary by Indu, Uttartantra,3/19 Published by Chaukhamba Sanskrita Sansthana Varanasi 2006.pp.18.

Shastri AD, Editor, Sushruta Smhita, Hindi commentary, Uttartantra27,4-5. Reprint2013, Chaukhamba Sanskrita SansthanaVaranasi 2013,183.

Shastri L, Yogaratnakara, Vidyoniti hindi tika, Balroga chikitsa adhyaya, Published by Chaukhamba pakashana, Varanasi,2017.pp.447. 20.

Tewari P.V, Kashyapa Samhita or Vriddhajivaka Tantra, Sutrasthana27/56 Published by Chaukhambha Vishwabharati Prakashana Varanasi 2016.pp.46.

DineshK.S. Baalagraha. In: Dinesh,K.S (ed.) Kaumarabhr tya Updated: Chaukhambha Publications; 2014.pp. 409- 410.

Kumar S.R Acharya’s Textbook of Kaumarbritya vol.1, Chaukhamba Orientalia, Varanasi.2009.pp.211-215. 17. Dinesh, In: Dinesh,K.S (ed.) Kaumarabhrtya: Chaukhamb ha Publications; 2014.pp. 412-413.

Kumar S.R, Acharya’s Textbook of Kaumarbritya vol.1., chpt. No.22.Chaukhamba Orientalia, Varanasi. 2008.pp.219.

Dinesh, K.S. Baalagraha. (ed.) Kaumarabhrtya Updated: Chaukhambha Publications; 2014. p. 413-414 20. Kumar S.R Acharya’s Textbook of Kaumarbritya vol.1. chpt. No.22.,Chaukhamba Orientalia, Varanasi.2009. p.no.251-252.

Dinesh,K.S. Baalagraha. , KaumarabhrtyaUpdated: Chauk hambha Publications; 2014. p. 414

Kumar S.R Acharya’s Textbook of Kaumarbritya vol.1. chpt. No.22.,Chaukhamba Orientalia, Varanasi.2009. p.no.253.

Dinesh,K.S. Baalagraha. In: Dinesh,K.S (ed.) Kaumarabh rtya Updated: Chaukhambha Publications; 2014. p. 414- 415

Kumar S.R Acharya’s Textbook of Kaumarbritya vol.1. chpt. No.22.,Chaukhamba Orientalia, Varanasi.2009. p.no.253.

Dinesh,K.S. Baalagraha. In: Dinesh,K.S (ed.) Kaumarabh rtya Updated: Chaukhambha Publications; 2014. p. 417 26. Kumar S.R Acharya’s Textbook of Kaumarbritya vol.1. chpt. No.22.,Chaukhamba Orientalia, Varanasi.2009. p.no.242.

Sharma, R.K. “Nidana Sthana, Prameha nidana,” in Agnivesa's Caraka Samhita. Varanasi, UP: Choukhamba Sanskrit Series Office, 2011.pp. 61–62.

Sharma, R.K. “Vimana Sthana, Jwara chikitsa,” in Agnivesa's Caraka Samhita. Varanasi, UP: Choukhamba Sanskrit Series Office, 2011.pp. 264-265.

Sharma, R.K. “Chikitsa Sthana, Kushta chikitsa,” in Agnivesa's Caraka Samhita. Varanasi, UP: Choukhamba Sanskrit Series Office, 2011.pp. 328.

Sharma, R.K. “Chikitsa Sthana, Unmada chikitsa,” in Agnivesa's Caraka Samhita. Varanasi, UP: Choukhamba Sanskrit Series Office, 2011.pp.420-421

Sharma, R.K. “Chikitsa Sthana, Arsa chikitsa,” in Agnivesa's Caraka Samhita. Varanasi, UP: Choukhamba Sanskrit Series Office, 2011. pp.583-584

Murthy, K.R. Srikantha. “Nidana Sthana, Raktapitta Nidanam.” Vagbhata's Ashtanga Hridayam, vol. 2, Chowkhamba Krishnadas Academy, Varanasi, UP, 2012, pp. 30–31.

Murthy, K.R. Srikantha. “Nidana Sthana, Mutraghata Nidanam.” Vagbhata's Ashtanga Hridayam, vol. 2, Chowkhamba Krishnadas Academy, Varanasi, UP, 2012, pp. 85

Murthy, K.R. Srikantha. “Nidana Sthana, Mutraghata Nidanam.” Vagbhata's Ashtanga Hridayam, vol. 2, Chowkhamba Krishnadas Academy, Varanasi, UP, 2012, pp. 90

Murthy, K.R. Srikantha. “Nidana Sthana, Panduroga Sopha-Visarpa Nidanam.” Vagbhata's Ashtanga Hridayam, vol. 2, Chowkhamba Krishnadas Academy, Varanasi, UP, 2012, pp. 124

Shirasu M, Touhara K. The scent of disease: Volatile organic compounds of the human body related to disease and disorder. J Biochem. 2011;150(3):257–66.

Mougang YK, Di Zazzo L, Minieri M, Capuano R, Catini A, Legramante JM, Paolesse R, Bernardini S, Di Natale C. Sensor array and gas chromatographic detection of the blood serum volatolomic signature of COVID-19. Iscience. 2021 Aug 20;24(8):102851.

Chen H, Qi X, Ma J, Zhang C, Feng H, Yao M. Breath borne VOC biomarkers for COVID-19. MedRxiv. 2020 Jan 1.

Giovannini G, Haick H, Garoli D. Detecting COVID-19 from breath: a game changer for a big challenge. ACS sensors. 2021 Apr 7;6(4):1408-17.

Shan B, Broza YY, Li W, Wang Y, Wu S, Liu Z, Wang J, Gui S, Wang L, Zhang Z, Liu W. Multiplexed nanomaterial-based sensor array for detection of COVID 19 in exhaled breath. ACS nano. 2020 Aug 18;14(9):12125-32.

Chen H, Qi X, Zhang L, Li X, Ma J, Zhang C, Feng H, Yao M. COVID-19 screening using breath-borne volatile organic compounds. Journal of breath research. 2021 Oct 22;15(4):047104.