Phytochemical Analysis And Standardization of Pathyadi Ghana Vati - An Ayurvedic Polyherbal Formulation For Migraine

Abstract

Background: Migraine is a common neurovascular ailment with a significant impact on quality of  life. It simulates with the Shiroroga (diseases of head) called Ardhavbhedaka in Ayurveda. Pathyadi  Kwatha is a very famous and commonly prescribed classical formulation in Ardhavbhedaka and  various other types of headache. Despite the fact that the formulation is mentioned in the classical texts  in the form of Kwatha (decoction), it was converted to the tablet (Ghana Vati) form as it is palatable,  easy to dispense, and has prolonged shelf life.  Objective and methods: The present study was designed to standardize the finished product, Pathyadi  Ghana Vati, by evaluation of its organoleptic, Physico-chemical, phytochemical and chromatographic  parameters. Results: Physico-chemical analysis revealed pH value 7.0, Alcohol soluble extract 29.10%, water soluble extract 82.05 %, Ash value 2.15%, and phytochemical analysis showed the presence of  alkaloids, amino acids, saponins, phenolic compound, and tannins.  Conclusion: The parameters presented in this paper may serve as a standard reference for the quality  control analysis of Pathyadi Ghana Vati.