A Clinical Trial to Determine the Efficacy of Abhaya Nagara Churna in the Management of Tamaka Swasa~Bronchial Asthma
Keywords:Abhaya Nagara Churna, Bronchial Asthma, Tamaka Swasa
Background: Tamaka Swasa is the manifestation of vitiated Kapha and Vata Dosha in the form of various symptoms such as Swasakrucchrata, Kasa, and Pinasa, which are associated with vitiation of Pranavaha Srotas. It shares various similarities with Bronchial Asthma which is an airway disease manifesting as recurrent episodes of dyspnea, cough, nasal congestion, and wheezing.
Objective: This study was aimed to evaluate the effectiveness of Abhaya Nagara Churna in improving the value
of symptom severity score of five major symptoms of Tamaka Swasa along with the action of drug in reduction of inhaler use and diurnal symptom frequency reduction.
Material and Methods: The study was single-centered and open-label clinical trial involving participation of 30 subjects diagnosed with asthma and fulfilling the conditions mentioned in inclusion criteria. Patients were administered Abhaya-Nagara Churna for 28 days in 3:1 ratio twice daily with warm water after every meal. Evaluation of Inhaler use frequency, nocturnal and daytime symptom frequency, and symptom severity were done and observations were drawn using suitable statistical tests.
Results: The observation on the various parameters established a statistically significant improvement in all parameters with p-value and percentage relief for Swasa Vega (Frequency) as 0.00057 and 10.64% respectively, for Swasa Vega (Duration) 0.0000023 and 50%, for Swasa Vega (Intensity) 0.0000083 and 32.05%, for Swasakrucchrata 0.0832 and 10.34% and for Ghurghurakama 0.00000273 and 73.33%, for Asino Labhate Saukhayama 0.00010 and 93.75%, for Kasa 0.00000096 and 96%, for Inhaler Use 0.000059 and 23.36%, for nocturnal symptoms 0.000013 and 38.10%, for daytime symptoms 0.000028 and 22.83%. P < 0.5 for all assessment criteria except for Swasakrucchrata, is signifying significant effect of drugs on all diagnostic parameters.
Conclusion: It is concluded that Abhaya-Nagara Churna effectively counters the symptomatic component of Tamaka Swasa along with improving overall quality of life in patients.